fig2

Figure 2. Overview of the main emerging features of EVs as sncRNA delivery systems in the 74 works analyzed. Pie charts illustrating the percentage (%) of EV donor cells used (A - the inset on the right represents a focus on the % of different stem cell types), surface engineering (B), type of non-coding RNA loaded (C), and evidence of sncRNA efficacy provided in the study (D). sncRNAs: Small non-coding RNAs; EVs: extracellular vesicles; EV: extracellular vesicle.