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Figure 1. (A) Schematic illustration of the fabrication process of the sacrificial PVB nanofiber-based nanomesh electrode; (B) Schematic illustration of the ethanol-triggered in-situ interfacial reconstruction process on human skin, including wetting, capillary infiltration, nanofiber dissolution, and interface reconstruction, leading to an air-gap-free and conformal epidermal electrode; (C) Surface and (D) cross-sectional morphology of nanomesh electrode before and after the interfacial reconstruction process; (E) Photograph of the nanomesh electrode reconstructed directly on human skin, and the enlarged view of the boundary between skin and nanomesh electrode; (F) Summary of key performance metrics of the nanomesh electrode, including conformality, low interfacial impedance, strong adhesion, high breathability, water resistance, and ethanol-assisted removability; (G) Illustration of the conformal electrode for continuous biopotential signal measurement. PVB: Poly(vinyl butyral); AgNWs: silver nanowires; EOG: electrooculography; EEG: electroencephalography; ECG: electrocardiography; EMG: electromyography.