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Effects of FAP+ cancer-associated fibroblasts on anti-PD-1 immunotherapy and CD4+ T cell polarization in gastric cancer
Open Access Original Article 28 Jul 2025
DOI: 10.20517/cdr.2025.97
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Super-enhancer inhibitors THZ2 and JQ1 reverse temozolomide resistance in glioblastoma by suppressing SE-driven SOX9 expression
Open Access Original Article 21 Jul 2025
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Decoding breast cancer treatment resistance through genetic, epigenetic, and immune-regulatory mechanisms: from molecular insights to translational perspectives
Open Access Review 20 Jul 2025
DOI: 10.20517/cdr.2025.69
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CF10/LV overcomes acquired resistance to 5-FU/LV in colorectal cancer cells through downregulation of the c-Myc/ABCB5 axis
Open Access Original Article 14 Jul 2025
DOI: 10.20517/cdr.2025.76
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The next frontier in antibody-drug conjugates: challenges and opportunities in cancer and autoimmune therapy
Open Access Review 2 Jul 2025
DOI: 10.20517/cdr.2025.49
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Interactions between tumor microenvironment and resistance to transarterial and systemic treatments for HCC
Open Access Review 1 Jul 2025
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Modeling methods of different tumor organoids and their application in tumor drug resistance research
Open Access Review 30 Jun 2025
DOI: 10.20517/cdr.2025.34
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Integrated multi-omics profiling of immune microenvironment and drug resistance signatures for precision prognosis in prostate cancer
Open Access Original Article 24 Jun 2025
DOI: 10.20517/cdr.2025.47
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MicroRNA-mediated autophagy regulation in thyroid cancer drug resistance
Open Access Mini Review 17 Jun 2025
DOI: 10.20517/cdr.2025.73
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Antibody-drug conjugates in breast cancer: current resistance mechanisms and future combination strategies
Open Access Review 16 Jun 2025
DOI: 10.20517/cdr.2025.26
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Fibroblast growth factor receptor alterations and resistance mechanisms in the treatment of pediatric solid tumors
Open Access Original Article 5 Jun 2025
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Acquired resistance to molecularly targeted therapies for cancer
Open Access Review 4 Jun 2025
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PER2 expression and cellular localization play a critical role in tumor aggressiveness and drug resistance in an in vitro model of hepatocellular carcinoma
Open Access Original Article 2 Jun 2025
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ZEB2 upregulation modulates the polarization of TAMs toward the immunosuppressive state in EGFR-TKI-resistant NSCLC
Open Access Original Article 28 May 2025
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Advances in the application of patient-derived xenograft models in acute leukemia resistance
Open Access Review 27 May 2025
DOI: 10.20517/cdr.2025.18
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FGFR1 overexpression promotes resistance to PI3K inhibitor alpelisib in luminal breast cancer cells through receptor tyrosine kinase signaling-mediated activation of the estrogen receptor
Open Access Original Article 27 May 2025
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Unveiling MAGEA3: a novel predictive biomarker for bevacizumab resistance in colorectal cancer
Open Access Original Article 27 Apr 2025
DOI: 10.20517/cdr.2025.35
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Ivosidenib enhances cisplatin sensitivity in ovarian cancer by reducing cancer cell stemness
Open Access Original Article 23 Apr 2025
DOI: 10.20517/cdr.2025.51
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